you will HAVE TO contact the seller if you are going to transfer their license. apple will need all their info in order to prove its legal in the first place, then they will be able to cancel theirs and allow you to validate yours.
just FYI, simply buying a computer with a program on it doesnt mean that you now own that installed program. unless, the seller goes through the process of unregistering and or transferring - its legall still their program.
this misconception catches a lot of folks by surprise...
changing the registration of the machine isnt really neccessary unless your transferring warranty/applecare service. BUT its best to blank ANY new machine and do a clean install of the OS and your apps. and then you can register everything cleanly