Technically, no. If they're not spinning, the operating system will not try to mount and manage them, but you have to use them in order. You can't use the one on the end and leave the ones in the middle turned off.
Each drive represents a discontinuity in the cable and reduces the speed of the transfer. When they're running, the internal electronics prevent that, but then cause other problems.
Buy cheap FireWire cards for each drive and one on the machine.
Koz