OK, solved. I had just hooked up a FW800 to a FW800 card separate from any 400 drives, to write the render files to. When FCP played media from the SATA it choked, thus my belief that something was wrong with the SATA, but those files had render files written to the FW800 drive. Once I unhooked the 800 drive the problems disappeared. I'm still not sure why a FW800 drive with render files wouldn't play nice with high speed SATA footage?