make sure all the "include.. such & such " tick boxes are un-ticked.
if you still dont get a significant reduction (sounds like a furniture wareouse ad!)
you have 2 options:
1- control or right clock on your sequence in the browser,
chose: "make sequence clips independent"
you may not want to make your seq clips independent.
so option 2
copy the sequence into a new project.
that'll sever the master / affiliate ties,
with out damaging your original seq.
cheers,
nick