Sorry if this is old hat but I was fooling around and I came across this interesting behaviour.
If you have to make a sequence with a high count of discrete channels (Stereo,5.1, M&E etc) It can be a pain modifying all 24 sequence track to go to the 24 different outputs.
You can however, starting from a blank sequence, reduce the number of tracks to just one audio track, change the output settings of the sequence (Apple-0, Audio Outputs Tab) to your desired number of outputs, add the number of tracks you need (Sequence/Insert Tracks) and it will add them 1:1, that is, track 1 to output 1, track 2 to output 2.
You can then edit your sequence over to this new sequence and prepare it for output.
Make sure your Audio output is set to "Discrete Channels" in the sequence settings (Apple-0)
Extra Fun:
Make a blank sequence with the track/output arrangement that you require frequently. Export it as an XML. Save it somewhere handy or cloud-y. Import as needed.
ak
Sleeplings, AWAKE!